TMR Theory and Hypothesis

2020, Volume 3 Issue 3

TMR Theory and Hypothesis 系Traditional Medical Research子刊，关注传统医学和民族医学理论的现代研究。旨在发表将这两种理论与现代生物医学，物理学，化学和数学模型相结合的创新文章。目前已被ScienceOpen，Ingenta Connect，中国科技期刊数据库（CSTJ），超星期刊数据库和Google学术搜索、中国知网、EuroPub收录。

siRNA-LDH纳米偶联物治疗COVID-19的预期假说

COVID-19 is a devastating outbreak that has developed from December, 2019. SARS-CoV-2 is the causative  organism of this disease condition. However, as this is a novel virus human race do not know the curative measures  of this disease. They don’t know the treatment procedure but only few preventive measures are known to them. In  today’s era of nanotechnology, nanoparticles may be used to combat this disease condition. In this publication, a  hypothesis is drawn on a prospective therapeutic procedure to combat COVID-19. A nanoconjugate comprising of  siRNA and Layered double hydroxide may be used as an intranasal spray to treat this disease condition. Specific  siRNA sequence that will target the RNA sequence of the virus will help to resist the replication and infection of  the virus. As this nanoconjugate will not have any side effect it may become an optimum therapeutic measure for  COVID-19. 

关于顺势疗法原理的新解释

Homeopathy is approximately two hundred and fifty years old medical system. In homeopathy, extremely small  dose of original substances is used to treat diseases that produce similar symptoms of the disease. Therefore,  two principles of homeopathy are the law of similars and the law of minute dose. Hahnemann proposed that  similar symptoms produced by remedies occupy the space of the disease. Reaction or withdrawal effect of the  remedy goes against the symptoms of the disease and thus the disease is cured. Although similar substances are  used to treat diseases, some substances produce both similar and opposite symptoms of the disease. Again many  substances used in minute dose previously exist in the body as large doses. The other principles of homeopathy are  the law of chronic diseases and the law of vital force. Hahnemann considered psora or scabies like syphilis. Like  syphilis, he considered skin symptoms as primary symptoms and chronic diseases as secondary symptoms. On  the other hand, high potency homeopathic remedies do not contain any original substance to produce a reaction  or withdrawal effect and 'vital force' theory has been refuted in modern science. Therefore these two principles  have limitations too. Hahnemann proposed that water is able to retain the memory of the original substance.  Modern observers suggest that water can form nanoparticles like original substances. But there is no strong proof  that nanoparticles are found in bloodstream or breast milk. To explain homeopathy these limitations should be  amended. 

从三焦理论探讨类淋巴系统与阿尔兹海默病的相关性

Type of the lymphatic system is a new concept put forward by foreign scholars in recent years. It is similar to the  lymphatic system, is the brain of the internal fluid metabolism channel and its metabolites in the brain plays a  major role in the process of removal, sleep disorders in alzheimer's disease brain stroke, traumatic brain injury and  other central nervous system diseases. The Tri-jiao theory is a very important in traditional Chinese medicine plate  structure, it is from the function to traffic from running water channel, but still no definite conclusion on structure.  This paper attempts to explore the relationship between trioke and the lymphatic system and their influence on  Alzheimer's disease through modern medical research on the lymphatic system, so as to provide new inspirations  for the treatment of Alzheimer's disease.

小续命汤治疗中风疗效性的meta分析

Objective:To evaluate the clinical efficacy and safety of Xiaoxuming decoction(XXMD) in the treatment of  stroke. Methods: Randomized controlled trials of XXMD in the treatment of stroke was searched from January  1, 2015 to March 1, 2020. The data extraction and methodological quality evaluation were carried out by two  researchers according to the pre-established inclusion and exclusion criteria, and the final inclusion study was  analyzed by meta using Revman5.3. Results: 22 RCT literatures were included, with a total of 1947 cases.  Compared with the control group, the experimental group could reduce the score of NIHSS scale (95%CI (-3.37,- 2.19), P<0.001), stroke score (95%CI (-2.71,-1.85), P<0.001), and BI (95%CI (6.15,8.50, P<0.001). And the  effective rate of the experimental group was 3.58 times higher than that of the control group, and the difference  was statistically significant (95%CI (2.40,5.36), P=0.0001). Conclusion: XXMD combined with western  medicine is superior to western medicine in improving the symptoms of neurological deficit and living ability  and the effective rate of stroke. In terms of clinical effective rate, the effective rate of XXMD in acute stage is  1.02 times higher than that in non-acute stage. However, no improvement in efficiency was found after syndrome  differentiation. Future research may achieve higher efficacy in syndrome types other than Fengtanyuzu.

基于新型冠状病毒肺炎思探养阴化痰法

To explore the theoretical basis of nourishing yin and resolving phlegm method and the characteristics of stage drug use. Inquire literature and seek the internal relationship between phlegm, dampness, water, drink and body fluid, blood and yin essence, and to expound the theoretical basis and characteristics of nourishing yin and resolving phlegm method. We put forward that expectorant is the key to the diagnosis and treatment of corona virus disease 2019 (COVID-19) in traditional Chinese medicine. Phlegm, drinking, dampness, body fluid, blood, and yin essence belong to the category of yin. Clinical syndrome can be evaluated based on the degree of yin injury and phlegm dampness.